TIROFIBAN HYDROCHLORIDE MONOHYDRATE
Tirofiban hydrochloride monohydrate
CAS: 150915-40-5
Molecular Formula: C22H39ClN2O6S
TIROFIBAN HYDROCHLORIDE MONOHYDRATE - Names and Identifiers
TIROFIBAN HYDROCHLORIDE MONOHYDRATE - Physico-chemical Properties
| Molecular Formula | C22H39ClN2O6S |
| Molar Mass | 495.07 |
| Melting Point | 135-137°C |
| Boling Point | 611.7℃ at 760 mmHg |
| Solubility | DMSO: >12mg/mL at warmed to 60°C |
| Appearance | White solid |
| Color | white to beige |
| Merck | 14,9464 |
| Storage Condition | -20°C |
| In vitro study | Tirofiban (MK-383, Aggrastat) is a non-peptide derivative of tyrosine that selectively inhibits the GP-IIb/IIIa receptor and has the lowest effect on the vβ3 Vitronectin receptor. Tirofiban inhibited gel-filtered platelet aggregation induced by 10 μm ADP with an IC50 of 9 nM, but inhibited human umbilical vein adhesion to Vitronectin with an IC50 of 62 μmol/L, this is dependent on the vβ3 receptor. |
| In vivo study | Tirofiban(10 to 500 mg/kg or 10 micrograms/kg/min continuous intravenous infusion for 360 minutes) inhibits platelet aggregation with ADP and collagen in the canine model. Treatment of humans with Tirofiban at 0.15 μg/kg/min for 4 hours increased bleeding time 2.5-fold and inhibited 97% of ADP-induced platelet aggregation. |
TIROFIBAN HYDROCHLORIDE MONOHYDRATE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| WGK Germany | 3 |
TIROFIBAN HYDROCHLORIDE MONOHYDRATE - Introduction
Tirofiban hydrochloride monohydrate is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Generally white crystalline powder.
-Solubility: Soluble in water and organic solvents such as ethanol and dimethyl sulfoxide.
-Stability: Relatively stable under regular experimental conditions.
Use:
- Tirofiban hydrochloride monohydrate is an important organic synthesis intermediate, which has a wide range of uses in drug synthesis and biochemical research.
-It can be used to synthesize anti-tumor drugs, antiviral drugs and biologically active compounds.
Preparation Method:
-The compound is generally prepared by organic synthesis methods, which require a series of chemical reagents and reaction steps for synthesis. The specific preparation method can be found through literature, patents or related materials.
Safety Information:
-The safety of Tirofiban hydrochloride monohydrate depends on its chemical properties, preparation conditions and uses.
-During use, follow laboratory safety practices and avoid contact with skin, eyes and inhalation.
-for specific safety information and risk assessment, it is recommended to refer to the relevant safety data sheet (SDS) and the safety instructions provided by the chemical supplier.
Nature:
-Appearance: Generally white crystalline powder.
-Solubility: Soluble in water and organic solvents such as ethanol and dimethyl sulfoxide.
-Stability: Relatively stable under regular experimental conditions.
Use:
- Tirofiban hydrochloride monohydrate is an important organic synthesis intermediate, which has a wide range of uses in drug synthesis and biochemical research.
-It can be used to synthesize anti-tumor drugs, antiviral drugs and biologically active compounds.
Preparation Method:
-The compound is generally prepared by organic synthesis methods, which require a series of chemical reagents and reaction steps for synthesis. The specific preparation method can be found through literature, patents or related materials.
Safety Information:
-The safety of Tirofiban hydrochloride monohydrate depends on its chemical properties, preparation conditions and uses.
-During use, follow laboratory safety practices and avoid contact with skin, eyes and inhalation.
-for specific safety information and risk assessment, it is recommended to refer to the relevant safety data sheet (SDS) and the safety instructions provided by the chemical supplier.
Last Update：2024-04-09 15:16:34
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Spot supply
Product Name: Tirofiban hydrochloride monohydrate Visit Supplier Webpage Request for quotationCAS: 150915-40-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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